Hormonal Health Peptides
Peptides that regulate endocrine function and hormone signaling. Includes analogs of naturally occurring hormones and compounds that modulate the hypothalamic-pituitary axis.
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Abaloparatide
Abaloparatide: FDA-approved PTHrP(1-34) analog for osteoporosis. Covers ACTIVE trial results, bone mineral density effects, fracture reduction, and comparison with teriparatide.
ACE-031
ACE-031: ActRIIB-Fc myostatin inhibitor for muscle wasting. Covers mechanism, Duchenne dystrophy trials, dosing, side effects, and clinical status.
Albiglutide (Tanzeum)
Albiglutide (Tanzeum/Eperzan): albumin-fused GLP-1 receptor agonist by GSK. FDA approved 2014 for T2D, withdrawn 2017 due to commercial failure despite positive HARMONY Outcomes CV trial.
Bivamelagon
Bivamelagon (LB54640): first oral MC4R agonist for hypothalamic obesity by Rhythm Pharmaceuticals. Phase 2 showed 9.3% BMI reduction at 14 weeks.
Exenatide
Exenatide: the first GLP-1 receptor agonist ever approved, derived from Gila monster venom. Covers EXSCEL cardiovascular trial, Byetta/Bydureon dosing, and neuroprotection research.
Gonadorelin
Gonadorelin (GnRH): Hypothalamic reproductive hormone guide. Covers HPG axis regulation, LH/FSH pulsatile release, fertility applications, and dosing.
HCG
HCG: Human chorionic gonadotropin for fertility and testosterone. Covers LH-mimetic mechanism, treatment protocols, dosing, and FDA indications.
HMG
HMG: Human menopausal gonadotropin for fertility treatment. Covers dual FSH/LH activity, IVF stimulation, Menopur dosing, and recombinant FSH comparison.
Insulin
Insulin: Essential glucose-regulating peptide hormone. Covers beta cell secretion, diabetes treatment types, rapid vs long-acting dosing, and safety.
Kisspeptin
Kisspeptin: Master HPG axis regulator for fertility research. Covers GnRH neuron activation, Phase 2 trial data, IVF applications, and safety.
LIB-01
LIB-01: first-in-class oral MC4R-modulating compound for erectile dysfunction by Dicot Pharma. Phase 2a results, unique month-long duration of action from 3-day dosing.
Mazdutide
Mazdutide: Dual GLP-1/glucagon agonist approved in China for obesity. Covers up to 20% weight loss in trials, mechanism, dosing, and side effects.
MVT-602
MVT-602: kisspeptin receptor agonist for IVF oocyte maturation trigger. Phase 2a results, prolonged LH surge, and OHSS risk reduction potential.
Oxytocin
Oxytocin: FDA-approved neuropeptide for labor and social bonding. Covers bonding mechanisms, anxiety research, intranasal delivery, and Pitocin dosing.
Pramlintide (Symlin)
Pramlintide (Symlin): FDA-approved synthetic amylin analog for type 1 and type 2 diabetes. Adjunct to mealtime insulin for postprandial glucose control with weight loss benefit.
Setmelanotide (IMCIVREE)
Setmelanotide (IMCIVREE): FDA-approved MC4R agonist for rare genetic obesity due to POMC, PCSK1, or LEPR deficiency. First-in-class targeted therapy for monogenic obesity.
Taspoglutide
Taspoglutide: once-weekly GLP-1 receptor agonist by Roche/Ipsen. Phase 3 T-emerge trials halted in 2010 due to severe GI side effects and hypersensitivity reactions.
Teriparatide
Teriparatide: FDA-approved recombinant PTH(1-34) for osteoporosis. Covers Fracture Prevention Trial results, glucocorticoid-induced osteoporosis data, and comparison with abaloparatide.
Triptorelin
Triptorelin: FDA-approved GnRH agonist for prostate cancer and endometriosis. Covers pituitary desensitization, depot formulations, dosing, and safety.
Head-to-Head Comparisons
Detailed comparisons between hormonal health peptides covering mechanisms, efficacy, side effects, and research evidence.
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Research guide covering peptides studied for menopause symptoms including hot flashes, bone loss, cognitive changes, skin aging, sleep disruption, and hormonal regulation.
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Peptides for bone health -- teriparatide, abaloparatide, BPC-157, and GHK-Cu reviewed with mechanisms, evidence levels, FDA approval status, and key research findings for osteoporosis and bone healing.
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Research review of peptides targeting sarcopenia and age-related muscle loss, including myostatin inhibitors, growth factors, and GH secretagogues with clinical trial data.
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Comprehensive guide to peptides for muscle growth and preservation — myostatin inhibitors (follistatin, bimagrumab, trevogrumab, apitegromab), IGF-1 pathway (IGF-1 LR3, MGF), and growth hormone secretagogues (ibutamoren, HGH) with clinical evidence and body recomp strategies.
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Myostatin inhibitors and muscle growth peptides — follistatin, ACE-031, GDF-8, IGF-1 LR3, and MGF — mechanisms and clinical evidence.
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A research review of non-GLP-1 peptide approaches to weight loss — amylin analogs (cagrilintide, petrelintide, pramlintide), melanocortin agonists (setmelanotide, bivamelagon), and anti-myostatin antibodies (bimagrumab).
Research Tools
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