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🧬Peptide Protocol Wiki

Anti-aging Peptides

Explore our collection of anti-aging peptides with comprehensive research-backed information.

Anti-Aging & LongevityWeight Loss & Metabolism

5-Amino-1MQ

5-Amino-1MQ is a selective NNMT inhibitor that boosts NAD+ levels. Preclinical data shows anti-obesity and muscle function benefits. No human trials published.

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Anti-Aging & LongevityWeight Loss & Metabolism

Carnosine

Carnosine: endogenous dipeptide with anti-glycation, antioxidant, and pH-buffering properties. Phase 2 trials in diabetes, cognition, and anti-aging applications.

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Growth HormoneAnti-Aging & Longevity

CJC-1295 DAC

CJC-1295 DAC: Long-acting GHRH analog with extended half-life. Covers Drug Affinity Complex mechanism, GH/IGF-1 elevation, dosing, and side effects.

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Growth HormoneAnti-Aging & Longevity

CJC-1295 without DAC

CJC-1295 No DAC (Mod GRF 1-29): Short-acting GHRH analog. Covers pulsatile GH release, Ipamorelin stack synergy, dosing, and side effects.

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Muscle & Bone HealthAnti-Aging & Longevity

Enobosarm

Enobosarm (Ostarine/GTx-024): oral SARM for muscle preservation during GLP-1 weight loss. QUALITY Phase 2b positive. PLATEAU trial with tirzepatide planned.

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Anti-Aging & LongevityImmune Support

Epitalon

Epitalon: Telomerase-activating anti-aging tetrapeptide. Covers telomere elongation, pineal gland modulation, Khavinson research, and dosing data.

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Anti-Aging & LongevityImmune Support

FOXO4-DRI

FOXO4-DRI: Senolytic peptide targeting senescent cells. Covers FOXO4-p53 disruption, aging reversal research by Baar et al., dosing, and limitations.

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Healing & Tissue RepairAnti-Aging & LongevitySkin & Hair

GHK-Cu

GHK-Cu: Copper tripeptide for skin healing and anti-aging. Covers collagen stimulation, wound repair, hair growth, and topical vs injectable use.

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Immune SupportAnti-Aging & Longevity

Glutathione

Glutathione: The body's master antioxidant tripeptide. Covers redox cycling, detoxification, immune support, IV vs oral bioavailability, and dosing.

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Anti-Aging & LongevityBrain & Neuroprotection

Humanin

Humanin: 24-amino acid mitochondrial-derived peptide with anti-apoptotic and neuroprotective effects. Research in Alzheimer's, aging, and metabolic disease.

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Growth HormoneAnti-Aging & Longevity

Ipamorelin

Ipamorelin: Selective GH secretagogue without cortisol/prolactin spikes. Covers GHSR mechanism, clinical research, dosing protocols, and side effects.

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Anti-Aging & LongevityBrain & Neuroprotection

Klotho Peptides

Klotho peptides (KP1, KP6) are synthetic fragments of the alpha-klotho anti-aging protein. Research covers kidney fibrosis, diabetic nephropathy, FGF23/FGF21 signaling, cognitive enhancement, and neuroprotection in preclinical models.

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Anti-Aging & LongevityCognitive EnhancementMitochondrial & Cellular Energy

NAD+

NAD+ (Nicotinamide Adenine Dinucleotide): Essential coenzyme for cellular energy, DNA repair, and anti-aging research. Covers sirtuins, PARPs, CD38, NAD+ decline with aging, precursor strategies, and clinical evidence.

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Anti-Aging & LongevitySkin & Hair

OS-01 (Peptide 14)

OS-01 (Peptide 14) is a senotherapeutic decapeptide targeting cellular senescence via PP2A modulation. Published RCT data shows skin barrier and aging improvements.

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Cognitive EnhancementAnti-Aging & Longevity

Pinealon

Pinealon (EDR): Bioregulatory neuroprotective tripeptide. Covers epigenetic gene regulation, cognitive enhancement research, and Khavinson science.

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Anti-Aging & LongevityImmune Support

PNC-27

PNC-27: p53-derived anticancer peptide guide. Covers selective HDM-2 binding on cancer membranes, pore-forming cytotoxicity, and research limitations.

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Growth HormoneAnti-Aging & Longevity

Sermorelin

Sermorelin: GHRH(1-29) analog for growth hormone stimulation. Covers pulsatile GH release, anti-aging research, dosing, and GH secretagogue comparison.

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Skin & HairAnti-Aging & Longevity

SNAP-8

SNAP-8: Botox-like cosmeceutical peptide for wrinkle reduction. Covers SNARE complex inhibition, topical formulation research, and Argireline comparison.

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Mitochondrial & Cellular EnergyAnti-Aging & LongevityVascular & Cardiovascular

SS-31

SS-31 (Elamipretide): Cardiolipin-targeting mitochondrial peptide. Covers Barth syndrome Phase 3 data, heart failure research, dosing, and trial results.

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Anti-Aging & LongevityImmune Support

Tat-Beclin-1

Tat-Beclin-1: cell-permeable autophagy-inducing peptide from beclin 1/HIV Tat. Preclinical antiviral, anticancer, and neuroprotective research applications.

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Immune SupportAnti-Aging & Longevity

Thymalin

Thymalin: Thymic peptide bioregulator for immune restoration. Covers T-cell support, pineal-thymic axis aging research, Khavinson studies, and dosing.

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Anti-Aging & LongevityImmune Support

Vilon

Vilon (Lys-Glu): synthetic dipeptide bioregulator with immunomodulatory and geroprotective effects. Preclinical research in lifespan extension and chromatin reactivation.

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Head-to-Head Comparisons

Detailed comparisons between anti-aging peptides covering mechanisms, efficacy, side effects, and research evidence.

Related Articles

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The Hallmarks of Aging: Which Peptides Target Which?

Definitive mapping of the 12 hallmarks of aging to specific peptide interventions including Epitalon, FOXO4-DRI, SS-31, MOTS-c, and NAD+.

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13 Best Anti-Aging Peptides (2026): Ranked by Clinical Evidence

From senolytic FOXO4-DRI to mitochondrial SS-31, we ranked 13 anti-aging peptides by clinical trial evidence across 6 mechanisms. See which have human data vs. animal-only studies.

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Peptides for Energy and Mitochondrial Health: What the Research Shows

Research guide to 7 peptides targeting energy and mitochondrial health — SS-31 (elamipretide), MOTS-c, humanin, carnosine, thymosin alpha-1, tesamorelin, and sermorelin — with clinical evidence, mechanisms, and practical context.

guide

Peptides for Physical Performance and Endurance: What the Research Shows

An evidence-based guide to peptides studied for physical performance, endurance, and exercise capacity — including MOTS-c, carnosine, tesamorelin, AOD-9604, cortistatin, and BPC-157.

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Growth Hormone Peptides for Beginners: Which Secretagogue Is Right for You?

A beginner-friendly guide to growth hormone secretagogues including ipamorelin, sermorelin, CJC-1295, and more. Learn how GH peptides work, compare options, and understand which secretagogue may fit your research goals.

comparison

Ipamorelin vs CJC-1295 vs Sermorelin: Which GH Peptide Stack Works Best?

A detailed three-way comparison of ipamorelin, CJC-1295, and sermorelin covering mechanisms, half-lives, side effects, stacking rationale, and clinical evidence to help researchers evaluate the best GH peptide combination.

Research Tools

Use our interactive tools to explore anti-aging peptides further.