Melanotan-2 Dosing Calculator
Melanotan-2: Cyclic melanocortin peptide for tanning and sexual function.
Pre-filled with the most-reported community reconstitution protocol for Melanotan-2. See how 1 mL and 2 mL of bacteriostatic water change concentration and syringe-draw volume, then adjust the calculator below for your own vial.
Also available in these vial strengths
Same Melanotan-2 protocol, recalculated for each vial size â reconstitution volumes, concentrations, and syringe-draw units update automatically.
Quick answer · Community-reported standard
A 20 mg vial of Melanotan-2 reconstituted with 2 mL of bacteriostatic water yields a concentration of 10.00 mg/mL. At that concentration, a 250 mcg dose of Melanotan-2 equals 2.5 units on a U-100 insulin syringe (0.025 mL). Melanotan-2 is typically administered once daily via subcutaneous.
Melanotan-2 20 mg reconstitution and dosage: 1 mL vs 2 mL bac water
For a 20 mg vial of Melanotan-2, bacteriostatic water volume is flexible. Less water means higher concentration and smaller injection volumes; more water means lower concentration and easier dose precision. Both options below are valid for a 20 mg vial.
| BAC water added | Concentration | Volume per 250 mcg dose | Draw on U-100 syringe (units) |
|---|---|---|---|
| 1 mL | 20.00 mg/mL | 0.013 mL | 1.3 units |
| 2 mL | 10.00 mg/mL | 0.025 mL | 2.5 units |
Melanotan-2 dosage chart: per-injection to weekly total
Common Melanotan-2 protocol doses centered on the 250 mcg baseline (research range 0.25 mgâ0.5 mg), with weekly totals at once daily frequency.
| Dose level | Per injection | Frequency | Weekly total |
|---|---|---|---|
| Lower | 0.13 mg | Once daily | 0.88 mg |
| Baseline | 0.25 mg | Once daily | 1.75 mg |
| Higher | 0.38 mg | Once daily | 2.63 mg |
| Upper range | 0.5 mg | Once daily | 3.5 mg |
Weekly totals assume consistent once daily dosing. Adjust the calculator below for your specific vial size and dose.
Calculate your Melanotan-2 dose
Alternative Melanotan-2 protocols
Beyond the default above, Melanotan-2 is also reported in the following protocols. Use these as starting points and recalculate with the tool above.
Low-Dose Conservative Protocol
Community- Dose
- 0.1-0.25 mg
- Frequency
- Once daily
- Duration
- 3-4 weeks (loading), then biweekly maintenance
- Route
- Subcutaneous
Lower dose to minimize side effects (nausea, flushing); preferred by first-time users
Weight-Based Research Protocol
Community- Dose
- 0.01 mg/kg body weight
- Frequency
- Once daily
- Duration
- Up to 2 weeks
- Route
- Subcutaneous
Derived from clinical research dosing; approximately 0.7-0.8 mg/day for a 175 lb individual
Maintenance Protocol
Community- Dose
- 0.25-0.5 mg
- Frequency
- Once or twice weekly
- Duration
- Ongoing (during sun season)
- Route
- Subcutaneous
After achieving desired tan; reduced frequency to maintain pigmentation
Tanning (loading phase)
Clinical- Dose
- 0.25-0.5 mg subcutaneous
- Frequency
- Daily
- Duration
- 2-4 weeks
Start at 0.25 mg to assess tolerance; titrate up based on response and side effects
Tanning (maintenance)
Clinical- Dose
- 0.5-1.0 mg subcutaneous
- Frequency
- 1-2 times per week
- Duration
- Ongoing as desired
UV exposure enhances tanning effect but is not required
Melanotan-2 reconstitution & storage
Reconstitute lyophilized powder with bacteriostatic water; optimal stability at pH ~5; minimize phosphate buffer concentration; use polypropylene containers to avoid adsorption
Lyophilized powder stored at 2-8C; reconstituted solution refrigerated at 4C and used within 1 week; aqueous preparations limited to ~24 h at room temperature (t90 ~27 h at 25C); even refrigerated solutions accumulate degradants over months
Melanotan-2 dosing FAQ
How much bacteriostatic water should I add to a 20 mg vial of Melanotan-2?
The community standard is 2 mL of bacteriostatic water for a 20 mg Melanotan-2 vial. That gives a concentration of 10.00 mg/mL, so a 250 mcg dose is 2.5 units on a U-100 insulin syringe. Adding 1 mL instead doubles the concentration to 20.00 mg/mL and halves the draw to 1.3 units. Less water = smaller injection volume but harder to measure precisely.
How many syringe units is a 250 mcg dose of Melanotan-2?
On a standard U-100 insulin syringe, a 250 mcg dose of Melanotan-2 is 2.5 units when the 20 mg vial is reconstituted with 2 mL of bacteriostatic water (10.00 mg/mL). If you use 1 mL of bac water instead, draw 1.3 units (20.00 mg/mL).
What is the standard Melanotan-2 dose?
Community-reported protocols for Melanotan-2 typically use 0.25 mgâ0.5 mg once daily via Subcutaneous. 250 mcg is a common starting dose. Most commonly reported loading protocol; dose based on body weight; combined with UV exposure
How long does a vial of Melanotan-2 last at 250 mcg once daily?
A 20 mg vial of Melanotan-2 contains roughly 80 doses at 250 mcg per injection. At once daily dosing, that is approximately 80 days (about 11 weeks) of supply per vial. Reconstituted Melanotan-2 should generally be used within 28 days when refrigerated.
Where do you inject Melanotan-2?
Melanotan-2 is typically injected subcutaneous. Common sites reported in the literature and by users include: Abdomen (subcutaneous), Upper thigh (subcutaneous). Rotate sites with each injection to reduce localized irritation.
Can I use sterile water instead of bacteriostatic water for Melanotan-2?
Bacteriostatic water (containing 0.9% benzyl alcohol as a preservative) is strongly preferred for multi-dose vials like Melanotan-2 because it inhibits microbial growth and lets a single vial be used over multiple weeks. Sterile water has no preservative and should generally be reserved for single-use preparations only.
More on Melanotan-2
Melanotan-2 overview
Mechanism of action, primary uses, and research summary
Melanotan-2 dosing protocols
Full clinical and research-based dosing reference
Melanotan-2 community protocols
Real-world usage patterns from peptide communities
Melanotan-2 side effects
Reported adverse effects and safety considerations
Medical Disclaimer
This website is for educational and informational purposes only. The information provided is not intended to diagnose, treat, cure, or prevent any disease. Always consult with a qualified healthcare professional before using any peptide or supplement.