Melanotan-2 Dosing Calculator
Pre-filled with the most-reported community reconstitution protocol for Melanotan-2. See how 1 mL and 2 mL of bacteriostatic water change concentration and syringe-draw volume, then adjust the calculator below for your own vial.
Quick answer · Community-reported standard
A 10 mg vial of Melanotan-2 reconstituted with 2 mL of bacteriostatic water yields a concentration of 5.00 mg/mL. At that concentration, a 250 mcg dose of Melanotan-2 equals 5 units on a U-100 insulin syringe (0.050 mL). Melanotan-2 is typically administered once daily via subcutaneous.
Melanotan-2 reconstitution: 1 mL vs 2 mL bac water
Bacteriostatic water volume is flexible. Less water means higher concentration and smaller injection volumes; more water means lower concentration and easier dose precision. Both options below are valid for a 10 mg vial.
| BAC water added | Concentration | Volume per 250 mcg dose | Draw on U-100 syringe (units) |
|---|---|---|---|
| 1 mL | 10.00 mg/mL | 0.025 mL | 2.5 units |
| 2 mL | 5.00 mg/mL | 0.050 mL | 5 units |
Calculate your Melanotan-2 dose
Alternative Melanotan-2 protocols
Beyond the default above, Melanotan-2 is also reported in the following protocols. Use these as starting points and recalculate with the tool above.
Low-Dose Conservative Protocol
Community- Dose
- 0.1-0.25 mg
- Frequency
- Once daily
- Duration
- 3-4 weeks (loading), then biweekly maintenance
- Route
- Subcutaneous
Lower dose to minimize side effects (nausea, flushing); preferred by first-time users
Weight-Based Research Protocol
Community- Dose
- 0.01 mg/kg body weight
- Frequency
- Once daily
- Duration
- Up to 2 weeks
- Route
- Subcutaneous
Derived from clinical research dosing; approximately 0.7-0.8 mg/day for a 175 lb individual
Maintenance Protocol
Community- Dose
- 0.25-0.5 mg
- Frequency
- Once or twice weekly
- Duration
- Ongoing (during sun season)
- Route
- Subcutaneous
After achieving desired tan; reduced frequency to maintain pigmentation
Tanning (loading phase)
Clinical- Dose
- 0.25-0.5 mg subcutaneous
- Frequency
- Daily
- Duration
- 2-4 weeks
Start at 0.25 mg to assess tolerance; titrate up based on response and side effects
Tanning (maintenance)
Clinical- Dose
- 0.5-1.0 mg subcutaneous
- Frequency
- 1-2 times per week
- Duration
- Ongoing as desired
UV exposure enhances tanning effect but is not required
Melanotan-2 reconstitution & storage
Reconstitute lyophilized powder with bacteriostatic water; optimal stability at pH ~5; minimize phosphate buffer concentration; use polypropylene containers to avoid adsorption
Lyophilized powder stored at 2-8C; reconstituted solution refrigerated at 4C and used within 1 week; aqueous preparations limited to ~24 h at room temperature (t90 ~27 h at 25C); even refrigerated solutions accumulate degradants over months
Melanotan-2 dosing FAQ
How much bacteriostatic water should I add to a 10 mg vial of Melanotan-2?
The community standard is 2 mL of bacteriostatic water for a 10 mg Melanotan-2 vial. That gives a concentration of 5.00 mg/mL, so a 250 mcg dose is 5 units on a U-100 insulin syringe. Adding 1 mL instead doubles the concentration to 10.00 mg/mL and halves the draw to 2.5 units. Less water = smaller injection volume but harder to measure precisely.
How many syringe units is a 250 mcg dose of Melanotan-2?
On a standard U-100 insulin syringe, a 250 mcg dose of Melanotan-2 is 5 units when the 10 mg vial is reconstituted with 2 mL of bacteriostatic water (5.00 mg/mL). If you use 1 mL of bac water instead, draw 2.5 units (10.00 mg/mL).
What is the standard Melanotan-2 dose?
Community-reported protocols for Melanotan-2 typically use 0.25 mg–0.5 mg once daily via Subcutaneous. 250 mcg is a common starting dose. Most commonly reported loading protocol; dose based on body weight; combined with UV exposure
How long does a vial of Melanotan-2 last at 250 mcg once daily?
A 10 mg vial of Melanotan-2 contains roughly 40 doses at 250 mcg per injection. At once daily dosing, that is approximately 40 days (about 6 weeks) of supply per vial. Reconstituted Melanotan-2 should generally be used within 28 days when refrigerated.
Where do you inject Melanotan-2?
Melanotan-2 is typically injected subcutaneous. Common sites reported in the literature and by users include: Abdomen (subcutaneous), Upper thigh (subcutaneous). Rotate sites with each injection to reduce localized irritation.
Can I use sterile water instead of bacteriostatic water for Melanotan-2?
Bacteriostatic water (containing 0.9% benzyl alcohol as a preservative) is strongly preferred for multi-dose vials like Melanotan-2 because it inhibits microbial growth and lets a single vial be used over multiple weeks. Sterile water has no preservative and should generally be reserved for single-use preparations only.
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Medical Disclaimer
This website is for educational and informational purposes only. The information provided is not intended to diagnose, treat, cure, or prevent any disease. Always consult with a qualified healthcare professional before using any peptide or supplement.