LIB-01 Dosing Calculator
LIB-01: first-in-class oral MC4R-modulating compound for erectile dysfunction by Dicot Pharma.
Pre-filled with the most-reported clinical reconstitution protocol for LIB-01. See how 1 mL and 2 mL of bacteriostatic water change concentration and syringe-draw volume, then adjust the calculator below for your own vial.
Quick answer · Clinical protocol
A 15 mg vial of LIB-01 reconstituted with 2 mL of bacteriostatic water yields a concentration of 7.50 mg/mL. At that concentration, a 10 mg dose of LIB-01 equals 133.3 units on a U-100 insulin syringe (1.333 mL). LIB-01 is typically administered once daily.
LIB-01 reconstitution: 1 mL vs 2 mL bac water
Bacteriostatic water volume is flexible. Less water means higher concentration and smaller injection volumes; more water means lower concentration and easier dose precision. Both options below are valid for a 15 mg vial.
| BAC water added | Concentration | Volume per 10 mg dose | Draw on U-100 syringe (units) |
|---|---|---|---|
| 1 mL | 15.00 mg/mL | 0.667 mL | 66.7 units |
| 2 mL | 7.50 mg/mL | 1.333 mL | 133.3 units |
Calculate your LIB-01 dose
Alternative LIB-01 protocols
Beyond the default above, LIB-01 is also reported in the following protocols. Use these as starting points and recalculate with the tool above.
Erectile Dysfunction (Phase 1 -- Multiple Ascending Dose)
Clinical- Dose
- Multiple oral doses ranging from 10 mg to 150 mg daily for 3 consecutive days.
- Frequency
- Once daily for 3 consecutive days
- Duration
- 3-day treatment course; effects monitored for at least 28 days
MAD cohort demonstrated the unique pharmacodynamic profile with onset within 7 days and duration of at least 28 days. Erectile function improvements measured by IIEF-EF and RigiScan.
Erectile Dysfunction (Phase 2a)
Clinical- Dose
- 25 mg or 50 mg oral tablets daily for 3 consecutive days in men with mild to moderate ED.
- Frequency
- Once daily for 3 consecutive days
- Duration
- 3-day treatment course; efficacy monitored over 8 weeks
The 50 mg group showed an 8.5-point IIEF-EF improvement with 31% complete responders (IIEF-EF >25) vs 0% placebo. Effects sustained through week 8.
LIB-01 reconstitution & storage
LIB-01 is administered as an oral tablet. No reconstitution, mixing, or injection preparation is required. The formulation is LIB-01 monohydrate in tablet form.
Storage conditions for LIB-01 tablets have not been publicly disclosed by Dicot Pharma. As an investigational product, LIB-01 is only available through clinical trial supply chains with controlled storage and distribution.
LIB-01 dosing FAQ
How much bacteriostatic water should I add to a 15 mg vial of LIB-01?
The community standard is 2 mL of bacteriostatic water for a 15 mg LIB-01 vial. That gives a concentration of 7.50 mg/mL, so a 10 mg dose is 133.3 units on a U-100 insulin syringe. Adding 1 mL instead doubles the concentration to 15.00 mg/mL and halves the draw to 66.7 units. Less water = smaller injection volume but harder to measure precisely.
How many syringe units is a 10 mg dose of LIB-01?
On a standard U-100 insulin syringe, a 10 mg dose of LIB-01 is 133.3 units when the 15 mg vial is reconstituted with 2 mL of bacteriostatic water (7.50 mg/mL). If you use 1 mL of bac water instead, draw 66.7 units (15.00 mg/mL).
What is the standard LIB-01 dose?
Clinical protocols for LIB-01 typically use 10 mgâ150 mg once daily via subcutaneous injection. 10 mg is a common starting dose. Phase 1 SAD cohort evaluated safety and tolerability across a wide dose range. All doses were well tolerated.
How long does a vial of LIB-01 last at 10 mg once daily?
A 15 mg vial of LIB-01 contains roughly 1 doses at 10 mg per injection. At once daily dosing, that is approximately 1 days (about 0 weeks) of supply per vial. Reconstituted LIB-01 should generally be used within 28 days when refrigerated.
Where do you inject LIB-01?
LIB-01 is typically injected subcutaneously. Common sites reported in the literature and by users include: Not applicable -- LIB-01 is an oral tablet formulation. Rotate sites with each injection to reduce localized irritation.
Can I use sterile water instead of bacteriostatic water for LIB-01?
Bacteriostatic water (containing 0.9% benzyl alcohol as a preservative) is strongly preferred for multi-dose vials like LIB-01 because it inhibits microbial growth and lets a single vial be used over multiple weeks. Sterile water has no preservative and should generally be reserved for single-use preparations only.
More on LIB-01
Medical Disclaimer
This website is for educational and informational purposes only. The information provided is not intended to diagnose, treat, cure, or prevent any disease. Always consult with a qualified healthcare professional before using any peptide or supplement.