Neuropeptide Y Dosing Calculator
Neuropeptide Y (NPY): 36-amino acid endogenous peptide regulating stress resilience, appetite, and anxiety.
Pre-filled with the most-reported clinical reconstitution protocol for Neuropeptide Y. See how 1 mL and 2 mL of bacteriostatic water change concentration and syringe-draw volume, then adjust the calculator below for your own vial.
Also available in these vial strengths
Same Neuropeptide Y protocol, recalculated for each vial size — reconstitution volumes, concentrations, and syringe-draw units update automatically.
Quick answer · Clinical protocol
A 30 mg vial of Neuropeptide Y reconstituted with 2 mL of bacteriostatic water yields a concentration of 15.00 mg/mL. At that concentration, a 6.8 mg dose of Neuropeptide Y equals 45.3 units on a U-100 insulin syringe (0.453 mL). Neuropeptide Y is typically administered once daily.
Neuropeptide Y 30 mg reconstitution and dosage: 1 mL vs 2 mL bac water
For a 30 mg vial of Neuropeptide Y, bacteriostatic water volume is flexible. Less water means higher concentration and smaller injection volumes; more water means lower concentration and easier dose precision. Both options below are valid for a 30 mg vial.
| BAC water added | Concentration | Volume per 6.8 mg dose | Draw on U-100 syringe (units) |
|---|---|---|---|
| 1 mL | 30.00 mg/mL | 0.227 mL | 22.7 units |
| 2 mL | 15.00 mg/mL | 0.453 mL | 45.3 units |
Neuropeptide Y dosage chart: per-injection to weekly total
Common Neuropeptide Y protocol doses centered on the 6.8 mg baseline (research range 6.8 mg), with weekly totals at once daily frequency.
| Dose level | Per injection | Frequency | Weekly total |
|---|---|---|---|
| Lower | 3.4 mg | Once daily | 23.8 mg |
| Baseline | 6.8 mg | Once daily | 47.6 mg |
| Higher | 10.2 mg | Once daily | 71.4 mg |
| Upper range | 13.6 mg | Once daily | 95.2 mg |
Weekly totals assume consistent once daily dosing. Adjust the calculator below for your specific vial size and dose.
Calculate your Neuropeptide Y dose
Alternative Neuropeptide Y protocols
Beyond the default above, Neuropeptide Y is also reported in the following protocols. Use these as starting points and recalculate with the tool above.
Intranasal Stress Resilience Protocol
Community- Dose
- 1-5 mg
- Frequency
- Once daily
- Duration
- 2-4 weeks
- Route
- Intranasal
Adapted from preclinical and early clinical intranasal NPY studies; very limited community usage
Neuropeptide Y reconstitution & storage
Clinical trial formulations used NPY dissolved in saline for intranasal insufflation via atomizer device. Research-grade NPY should be reconstituted in sterile saline or PBS.
Store lyophilized NPY at -20 degrees C, protected from light and moisture. Reconstituted solutions should be used promptly or stored refrigerated at 2-8 degrees C for short-term use.
Neuropeptide Y dosing FAQ
How much bacteriostatic water should I add to a 30 mg vial of Neuropeptide Y?
The community standard is 2 mL of bacteriostatic water for a 30 mg Neuropeptide Y vial. That gives a concentration of 15.00 mg/mL, so a 6.8 mg dose is 45.3 units on a U-100 insulin syringe. Adding 1 mL instead doubles the concentration to 30.00 mg/mL and halves the draw to 22.7 units. Less water = smaller injection volume but harder to measure precisely.
How many syringe units is a 6.8 mg dose of Neuropeptide Y?
On a standard U-100 insulin syringe, a 6.8 mg dose of Neuropeptide Y is 45.3 units when the 30 mg vial is reconstituted with 2 mL of bacteriostatic water (15.00 mg/mL). If you use 1 mL of bac water instead, draw 22.7 units (30.00 mg/mL).
What is the standard Neuropeptide Y dose?
Clinical protocols for Neuropeptide Y typically use 6.8 mg once daily via subcutaneous injection. 6.8 mg is a common starting dose. Randomized controlled trial in MDD patients on stable antidepressants. Effects assessed up to 48 hours post-dose. Preliminary antidepressant effects observed.
How long does a vial of Neuropeptide Y last at 6.8 mg once daily?
A 30 mg vial of Neuropeptide Y contains roughly 4 doses at 6.8 mg per injection. At once daily dosing, that is approximately 4 days (about 1 weeks) of supply per vial. Reconstituted Neuropeptide Y should generally be used within 28 days when refrigerated.
Where do you inject Neuropeptide Y?
Neuropeptide Y is typically injected subcutaneously. Common sites reported in the literature and by users include: Intranasal (clinical trials), Intracerebroventricular (animal research), Intravenous (research). Rotate sites with each injection to reduce localized irritation.
Can I use sterile water instead of bacteriostatic water for Neuropeptide Y?
Bacteriostatic water (containing 0.9% benzyl alcohol as a preservative) is strongly preferred for multi-dose vials like Neuropeptide Y because it inhibits microbial growth and lets a single vial be used over multiple weeks. Sterile water has no preservative and should generally be reserved for single-use preparations only.
More on Neuropeptide Y
Neuropeptide Y overview
Mechanism of action, primary uses, and research summary
Neuropeptide Y dosing protocols
Full clinical and research-based dosing reference
Neuropeptide Y community protocols
Real-world usage patterns from peptide communities
Neuropeptide Y side effects
Reported adverse effects and safety considerations
Medical Disclaimer
This website is for educational and informational purposes only. The information provided is not intended to diagnose, treat, cure, or prevent any disease. Always consult with a qualified healthcare professional before using any peptide or supplement.