Neuropeptide Y Dosing Calculator
Pre-filled with the most-reported clinical reconstitution protocol for Neuropeptide Y. See how 1 mL and 2 mL of bacteriostatic water change concentration and syringe-draw volume, then adjust the calculator below for your own vial.
Quick answer · Clinical protocol
A 30 mg vial of Neuropeptide Y reconstituted with 2 mL of bacteriostatic water yields a concentration of 15.00 mg/mL. At that concentration, a 6.8 mg dose of Neuropeptide Y equals 45.3 units on a U-100 insulin syringe (0.453 mL). Neuropeptide Y is typically administered once daily.
Neuropeptide Y reconstitution: 1 mL vs 2 mL bac water
Bacteriostatic water volume is flexible. Less water means higher concentration and smaller injection volumes; more water means lower concentration and easier dose precision. Both options below are valid for a 30 mg vial.
| BAC water added | Concentration | Volume per 6.8 mg dose | Draw on U-100 syringe (units) |
|---|---|---|---|
| 1 mL | 30.00 mg/mL | 0.227 mL | 22.7 units |
| 2 mL | 15.00 mg/mL | 0.453 mL | 45.3 units |
Calculate your Neuropeptide Y dose
Alternative Neuropeptide Y protocols
Beyond the default above, Neuropeptide Y is also reported in the following protocols. Use these as starting points and recalculate with the tool above.
Intranasal Stress Resilience Protocol
Community- Dose
- 1-5 mg
- Frequency
- Once daily
- Duration
- 2-4 weeks
- Route
- Intranasal
Adapted from preclinical and early clinical intranasal NPY studies; very limited community usage
Neuropeptide Y reconstitution & storage
Clinical trial formulations used NPY dissolved in saline for intranasal insufflation via atomizer device. Research-grade NPY should be reconstituted in sterile saline or PBS.
Store lyophilized NPY at -20 degrees C, protected from light and moisture. Reconstituted solutions should be used promptly or stored refrigerated at 2-8 degrees C for short-term use.
Neuropeptide Y dosing FAQ
How much bacteriostatic water should I add to a 30 mg vial of Neuropeptide Y?
The community standard is 2 mL of bacteriostatic water for a 30 mg Neuropeptide Y vial. That gives a concentration of 15.00 mg/mL, so a 6.8 mg dose is 45.3 units on a U-100 insulin syringe. Adding 1 mL instead doubles the concentration to 30.00 mg/mL and halves the draw to 22.7 units. Less water = smaller injection volume but harder to measure precisely.
How many syringe units is a 6.8 mg dose of Neuropeptide Y?
On a standard U-100 insulin syringe, a 6.8 mg dose of Neuropeptide Y is 45.3 units when the 30 mg vial is reconstituted with 2 mL of bacteriostatic water (15.00 mg/mL). If you use 1 mL of bac water instead, draw 22.7 units (30.00 mg/mL).
What is the standard Neuropeptide Y dose?
Clinical protocols for Neuropeptide Y typically use 6.8 mg once daily via subcutaneous injection. 6.8 mg is a common starting dose. Randomized controlled trial in MDD patients on stable antidepressants. Effects assessed up to 48 hours post-dose. Preliminary antidepressant effects observed.
How long does a vial of Neuropeptide Y last at 6.8 mg once daily?
A 30 mg vial of Neuropeptide Y contains roughly 4 doses at 6.8 mg per injection. At once daily dosing, that is approximately 4 days (about 1 weeks) of supply per vial. Reconstituted Neuropeptide Y should generally be used within 28 days when refrigerated.
Where do you inject Neuropeptide Y?
Neuropeptide Y is typically injected subcutaneously. Common sites reported in the literature and by users include: Intranasal (clinical trials), Intracerebroventricular (animal research), Intravenous (research). Rotate sites with each injection to reduce localized irritation.
Can I use sterile water instead of bacteriostatic water for Neuropeptide Y?
Bacteriostatic water (containing 0.9% benzyl alcohol as a preservative) is strongly preferred for multi-dose vials like Neuropeptide Y because it inhibits microbial growth and lets a single vial be used over multiple weeks. Sterile water has no preservative and should generally be reserved for single-use preparations only.
More on Neuropeptide Y
Medical Disclaimer
This website is for educational and informational purposes only. The information provided is not intended to diagnose, treat, cure, or prevent any disease. Always consult with a qualified healthcare professional before using any peptide or supplement.