Dihexa Dosing Calculator
Dihexa (PNB-0408): angiotensin IV-derived peptide that potentiates HGF/c-Met signaling.
Pre-filled with the most-reported clinical reconstitution protocol for Dihexa. See how 1 mL and 2 mL of bacteriostatic water change concentration and syringe-draw volume, then adjust the calculator below for your own vial.
Quick answer · Clinical protocol
A 15 mg vial of Dihexa reconstituted with 2 mL of bacteriostatic water yields a concentration of 7.50 mg/mL. At that concentration, a 2 mg dose of Dihexa equals 26.7 units on a U-100 insulin syringe (0.267 mL). Dihexa is typically administered once daily.
Dihexa reconstitution: 1 mL vs 2 mL bac water
Bacteriostatic water volume is flexible. Less water means higher concentration and smaller injection volumes; more water means lower concentration and easier dose precision. Both options below are valid for a 15 mg vial.
| BAC water added | Concentration | Volume per 2 mg dose | Draw on U-100 syringe (units) |
|---|---|---|---|
| 1 mL | 15.00 mg/mL | 0.133 mL | 13.3 units |
| 2 mL | 7.50 mg/mL | 0.267 mL | 26.7 units |
Calculate your Dihexa dose
Alternative Dihexa protocols
Beyond the default above, Dihexa is also reported in the following protocols. Use these as starting points and recalculate with the tool above.
Low-Dose Oral Protocol
Community- Dose
- 5-10 mg
- Frequency
- Once daily
- Duration
- 4-8 weeks (with cycling)
- Route
- Oral
Starting dose for new users; taken orally based on reported oral bioavailability in animal studies
Moderate Oral Protocol
Community- Dose
- 10-20 mg
- Frequency
- Once daily
- Duration
- 4-8 weeks
- Route
- Oral
Dose used by more experienced users; some report diminishing returns above 20 mg
Sublingual Protocol
Community- Dose
- 5-10 mg
- Frequency
- Once daily
- Duration
- 4-8 weeks
- Route
- Sublingual
Some users try sublingual for potentially improved absorption; no data supporting this route
Cycling Protocol
Community- Dose
- 10-20 mg
- Frequency
- Once daily
- Duration
- 90 days on, 30 days off
- Route
- Oral
Extended cycling protocol; longer on-period due to proposed mechanism of promoting lasting structural changes (synaptogenesis)
Dihexa reconstitution & storage
As a research chemical, dihexa is typically supplied as a lyophilized powder. For research purposes, it is dissolved in DMSO for stock solutions or appropriate vehicle for animal studies. No standardized reconstitution protocol exists for human use.
Store lyophilized powder at -20 degrees C. Protect from light and moisture. Reconstituted solutions should be stored at 2-8 degrees C and used promptly. Long-term stability data for reconstituted solutions have not been published.
Dihexa dosing FAQ
How much bacteriostatic water should I add to a 15 mg vial of Dihexa?
The community standard is 2 mL of bacteriostatic water for a 15 mg Dihexa vial. That gives a concentration of 7.50 mg/mL, so a 2 mg dose is 26.7 units on a U-100 insulin syringe. Adding 1 mL instead doubles the concentration to 15.00 mg/mL and halves the draw to 13.3 units. Less water = smaller injection volume but harder to measure precisely.
How many syringe units is a 2 mg dose of Dihexa?
On a standard U-100 insulin syringe, a 2 mg dose of Dihexa is 26.7 units when the 15 mg vial is reconstituted with 2 mL of bacteriostatic water (7.50 mg/mL). If you use 1 mL of bac water instead, draw 13.3 units (15.00 mg/mL).
What is the standard Dihexa dose?
Clinical protocols for Dihexa typically use 2 mgâ2013 mg once daily via subcutaneous injection. 2 mg is a common starting dose. All dosing information is derived from animal studies. No human clinical trials have been conducted. Human-equivalent doses cannot be reliably calculated from these data.
How long does a vial of Dihexa last at 2 mg once daily?
A 15 mg vial of Dihexa contains roughly 7 doses at 2 mg per injection. At once daily dosing, that is approximately 7 days (about 1 weeks) of supply per vial. Reconstituted Dihexa should generally be used within 28 days when refrigerated.
Where do you inject Dihexa?
Dihexa is typically administered subcutaneously. Common subcutaneous sites are the lower abdomen (at least an inch from the navel), the outer thigh, and the love handles. Rotate sites with each injection to reduce localized irritation and bruising.
Can I use sterile water instead of bacteriostatic water for Dihexa?
Bacteriostatic water (containing 0.9% benzyl alcohol as a preservative) is strongly preferred for multi-dose vials like Dihexa because it inhibits microbial growth and lets a single vial be used over multiple weeks. Sterile water has no preservative and should generally be reserved for single-use preparations only.
More on Dihexa
Medical Disclaimer
This website is for educational and informational purposes only. The information provided is not intended to diagnose, treat, cure, or prevent any disease. Always consult with a qualified healthcare professional before using any peptide or supplement.