Nemifitide Dosing Calculator

Dose

0.2 mg/kg subcutaneous

Frequency

Daily

Duration

5 consecutive days

Significant antidepressant effects in patients achieving adequate plasma concentrations. Rapid onset within 5-7 days.

Dose

0.2 mg/kg subcutaneous

Frequency

Daily

Duration

10 consecutive days

Extended treatment course evaluated in some trials. Maintained safety profile with continued efficacy.

How much bacteriostatic water should I add to a 15 mg vial of Nemifitide?

The community standard is 2 mL of bacteriostatic water for a 15 mg Nemifitide vial. That gives a concentration of 7.50 mg/mL, so a 200 mcg dose is 2.7 units on a U-100 insulin syringe. Adding 1 mL instead doubles the concentration to 15.00 mg/mL and halves the draw to 1.3 units. Less water = smaller injection volume but harder to measure precisely.

How many syringe units is a 200 mcg dose of Nemifitide?

On a standard U-100 insulin syringe, a 200 mcg dose of Nemifitide is 2.7 units when the 15 mg vial is reconstituted with 2 mL of bacteriostatic water (7.50 mg/mL). If you use 1 mL of bac water instead, draw 1.3 units (15.00 mg/mL).

What is the standard Nemifitide dose?

Community-reported protocols for Nemifitide typically use 0.2 mg–14 mg once daily via Subcutaneous. 200 mcg is a common starting dose. Directly adapted from phase 2 clinical trial protocols; very few community users have attempted this

How long does a vial of Nemifitide last at 200 mcg once daily?

A 15 mg vial of Nemifitide contains roughly 75 doses at 200 mcg per injection. At once daily dosing, that is approximately 75 days (about 11 weeks) of supply per vial. Reconstituted Nemifitide should generally be used within 28 days when refrigerated.

Where do you inject Nemifitide?

Nemifitide is typically injected subcutaneous. Common sites reported in the literature and by users include: Subcutaneous (abdomen, thigh, or upper arm). Rotate sites with each injection to reduce localized irritation.

Can I use sterile water instead of bacteriostatic water for Nemifitide?

Bacteriostatic water (containing 0.9% benzyl alcohol as a preservative) is strongly preferred for multi-dose vials like Nemifitide because it inhibits microbial growth and lets a single vial be used over multiple weeks. Sterile water has no preservative and should generally be reserved for single-use preparations only.