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Melanotan-1 Dosing Calculator

Pre-filled with the most-reported community reconstitution protocol for Melanotan-1. See how 1 mL and 2 mL of bacteriostatic water change concentration and syringe-draw volume, then adjust the calculator below for your own vial.

Also available in these vial strengths

2 mg (current)5 mg vial10 mg vial

Same Melanotan-1 protocol, recalculated for each vial size — reconstitution volumes, concentrations, and syringe-draw units update automatically.

Quick answer · Community-reported standard

A 2 mg vial of Melanotan-1 reconstituted with 2 mL of bacteriostatic water yields a concentration of 1.00 mg/mL. At that concentration, a 500 mcg dose of Melanotan-1 equals 50 units on a U-100 insulin syringe (0.500 mL). Melanotan-1 is typically administered once daily via subcutaneous.

Melanotan-1 2 mg reconstitution and dosage: 1 mL vs 2 mL bac water

For a 2 mg vial of Melanotan-1, bacteriostatic water volume is flexible. Less water means higher concentration and smaller injection volumes; more water means lower concentration and easier dose precision. Both options below are valid for a 2 mg vial.

BAC water addedConcentrationVolume per 500 mcg doseDraw on U-100 syringe (units)
1 mL2.00 mg/mL0.250 mL25 units
2 mL1.00 mg/mL0.500 mL50 units
Based on a 2 mg vial of Melanotan-1 reconstituted with bacteriostatic water. Insulin-syringe units assume a standard U-100 syringe (100 units = 1 mL).

Melanotan-1 dosage chart: per-injection to weekly total

Common Melanotan-1 protocol doses centered on the 500 mcg baseline (research range 0.5 mg–1 mg), with weekly totals at once daily frequency.

Dose levelPer injectionFrequencyWeekly total
Lower0.25 mgOnce daily1.75 mg
Baseline0.5 mgOnce daily3.5 mg
Higher0.75 mgOnce daily5.25 mg
Upper range1 mgOnce daily7 mg

Weekly totals assume consistent once daily dosing. Adjust the calculator below for your specific vial size and dose.

Calculate your Melanotan-1 dose

Alternative Melanotan-1 protocols

Beyond the default above, Melanotan-1 is also reported in the following protocols. Use these as starting points and recalculate with the tool above.

Maintenance Protocol

Community
Dose
1.0-2.0 mg
Frequency
Once weekly
Duration
Ongoing (during sun season)
Route
Subcutaneous

After initial loading; approximately 8 mg per month for maintenance

Conservative Protocol

Community
Dose
0.5 mg
Frequency
Once daily
Duration
2-3 weeks then biweekly
Route
Subcutaneous

Lower dose for gradual tanning with minimal side effects; preferred by those sensitive to nausea

EPP photoprotection (approved)

Clinical
Dose
16 mg subcutaneous implant
Frequency
Every 60 days
Duration
3-5 implants per year, seasonally adjusted

Administered by specialist physician via subcutaneous insertion

Research tanning protocol (investigational)

Clinical
Dose
0.16 mg/kg subcutaneous injection
Frequency
Daily for 10 days per cycle
Duration
10-day cycles repeated monthly for up to 3 months

SC bioavailability approximately 100% relative to IV

Melanotan-1 reconstitution & storage

Lyophilized powder reconstituted with sterile water or bacteriostatic water; peptide is most stable at acidic to neutral pH (avoid pH >8)

Lyophilized powder stored at 2-8C; reconstituted solution refrigerated and used within days; Ea ~15.8 kcal/mol supports significant stabilization with refrigeration

Melanotan-1 dosing FAQ

How much bacteriostatic water should I add to a 2 mg vial of Melanotan-1?

The community standard is 2 mL of bacteriostatic water for a 2 mg Melanotan-1 vial. That gives a concentration of 1.00 mg/mL, so a 500 mcg dose is 50 units on a U-100 insulin syringe. Adding 1 mL instead doubles the concentration to 2.00 mg/mL and halves the draw to 25 units. Less water = smaller injection volume but harder to measure precisely.

How many syringe units is a 500 mcg dose of Melanotan-1?

On a standard U-100 insulin syringe, a 500 mcg dose of Melanotan-1 is 50 units when the 2 mg vial is reconstituted with 2 mL of bacteriostatic water (1.00 mg/mL). If you use 1 mL of bac water instead, draw 25 units (2.00 mg/mL).

What is the standard Melanotan-1 dose?

Community-reported protocols for Melanotan-1 typically use 0.5 mg–1 mg once daily via Subcutaneous. 500 mcg is a common starting dose. Higher doses than MT-2 due to MC1R selectivity (less potent per mg); combined with moderate UV exposure

How long does a vial of Melanotan-1 last at 500 mcg once daily?

A 2 mg vial of Melanotan-1 contains roughly 4 doses at 500 mcg per injection. At once daily dosing, that is approximately 4 days (about 1 weeks) of supply per vial. Reconstituted Melanotan-1 should generally be used within 28 days when refrigerated.

Where do you inject Melanotan-1?

Melanotan-1 is typically injected subcutaneous. Common sites reported in the literature and by users include: Abdomen (subcutaneous), Upper arm (subcutaneous). Rotate sites with each injection to reduce localized irritation.

Can I use sterile water instead of bacteriostatic water for Melanotan-1?

Bacteriostatic water (containing 0.9% benzyl alcohol as a preservative) is strongly preferred for multi-dose vials like Melanotan-1 because it inhibits microbial growth and lets a single vial be used over multiple weeks. Sterile water has no preservative and should generally be reserved for single-use preparations only.

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Medical Disclaimer

This website is for educational and informational purposes only. The information provided is not intended to diagnose, treat, cure, or prevent any disease. Always consult with a qualified healthcare professional before using any peptide or supplement.