Triptorelin Dosing Calculator
Triptorelin: FDA-approved GnRH agonist for prostate cancer and endometriosis.
Pre-filled with the most-reported community reconstitution protocol for Triptorelin. See how 1 mL and 2 mL of bacteriostatic water change concentration and syringe-draw volume, then adjust the calculator below for your own vial.
Quick answer · Community-reported standard
A 5 mg vial of Triptorelin reconstituted with 1 mL of bacteriostatic water yields a concentration of 2.50 mg/mL. At that concentration, a 100 mcg dose of Triptorelin equals 4 units on a U-100 insulin syringe (0.040 mL). Triptorelin is typically administered once daily via intramuscular.
Triptorelin reconstitution: 1 mL vs 2 mL bac water
Bacteriostatic water volume is flexible. Less water means higher concentration and smaller injection volumes; more water means lower concentration and easier dose precision. Both options below are valid for a 5 mg vial.
| BAC water added | Concentration | Volume per 100 mcg dose | Draw on U-100 syringe (units) |
|---|---|---|---|
| 1 mL | 5.00 mg/mL | 0.020 mL | 2 units |
| 2 mL | 2.50 mg/mL | 0.040 mL | 4 units |
Calculate your Triptorelin dose
Alternative Triptorelin protocols
Beyond the default above, Triptorelin is also reported in the following protocols. Use these as starting points and recalculate with the tool above.
Low-Dose PCT Support Protocol
Community- Dose
- 50 mcg
- Frequency
- Single injection
- Duration
- One-time administration
- Route
- Intramuscular
Conservative single-dose approach for less severe suppression; combined with SERM PCT
Triptorelin + SERM Combined PCT
Community- Dose
- 100 mcg triptorelin + Clomid 25-50 mg daily
- Frequency
- Single triptorelin injection then daily SERM
- Duration
- Triptorelin once then 4-6 weeks SERM
- Route
- Intramuscular
Combined approach using triptorelin for initial GnRH stimulus followed by sustained SERM to prevent relapse
Advanced prostate cancer (1-month depot)
Clinical- Dose
- 3.75 mg triptorelin pamoate intramuscular injection
- Frequency
- Every 28 days (monthly)
- Duration
- Continuous until disease progression or treatment change
Co-administer anti-androgen for first 2-3 weeks to prevent testosterone flare; monitor testosterone and PSA levels
Advanced prostate cancer (3-month depot)
Clinical- Dose
- 11.25 mg triptorelin pamoate intramuscular injection
- Frequency
- Every 84 days (3 months)
- Duration
- Continuous until disease progression or treatment change
More convenient dosing schedule; verify castrate testosterone levels are maintained between injections
Advanced prostate cancer (6-month depot)
Clinical- Dose
- 22.5 mg triptorelin pamoate intramuscular injection
- Frequency
- Every 24 weeks (6 months)
- Duration
- Continuous until disease progression or treatment change
Maximum dosing interval; requires verification of sustained castrate testosterone levels throughout dosing period
Triptorelin reconstitution & storage
Triptorelin depot formulations are supplied as pre-filled syringes or as lyophilized microspheres requiring reconstitution with the provided diluent. Follow manufacturer instructions precisely. For microsphere formulations, add diluent to the vial, swirl gently until a uniform suspension forms, and inject immediately after reconstitution. Do not store reconstituted product.
Store triptorelin depot formulations at controlled room temperature (20-25 degrees Celsius) or refrigerated (2-8 degrees Celsius) depending on specific product. Protect from light. Do not freeze. Check specific product labeling for exact storage requirements as they may vary by formulation.
Triptorelin dosing FAQ
How much bacteriostatic water should I add to a 5 mg vial of Triptorelin?
The community standard is 1 mL of bacteriostatic water for a 5 mg Triptorelin vial. That gives a concentration of 2.50 mg/mL, so a 100 mcg dose is 4 units on a U-100 insulin syringe. Adding 1 mL instead doubles the concentration to 5.00 mg/mL and halves the draw to 2 units. Less water = smaller injection volume but harder to measure precisely.
How many syringe units is a 100 mcg dose of Triptorelin?
On a standard U-100 insulin syringe, a 100 mcg dose of Triptorelin is 4 units when the 5 mg vial is reconstituted with 1 mL of bacteriostatic water (2.50 mg/mL). If you use 1 mL of bac water instead, draw 2 units (5.00 mg/mL).
What is the standard Triptorelin dose?
Community-reported protocols for Triptorelin typically use 100 mcg once daily via Intramuscular. 100 mcg is a common starting dose. The "one-shot PCT" protocol; 100 mcg (NOT milligrams); used after all exogenous compounds have cleared
How long does a vial of Triptorelin last at 100 mcg once daily?
A 5 mg vial of Triptorelin contains roughly 50 doses at 100 mcg per injection. At once daily dosing, that is approximately 50 days (about 7 weeks) of supply per vial. Reconstituted Triptorelin should generally be used within 28 days when refrigerated.
Where do you inject Triptorelin?
Triptorelin is typically injected intramuscular. Common sites reported in the literature and by users include: Gluteal muscle (dorsogluteal), Deltoid muscle. Rotate sites with each injection to reduce localized irritation.
Can I use sterile water instead of bacteriostatic water for Triptorelin?
Bacteriostatic water (containing 0.9% benzyl alcohol as a preservative) is strongly preferred for multi-dose vials like Triptorelin because it inhibits microbial growth and lets a single vial be used over multiple weeks. Sterile water has no preservative and should generally be reserved for single-use preparations only.
More on Triptorelin
Triptorelin overview
Mechanism of action, primary uses, and research summary
Triptorelin dosing protocols
Full clinical and research-based dosing reference
Triptorelin community protocols
Real-world usage patterns from peptide communities
Triptorelin side effects
Reported adverse effects and safety considerations
Medical Disclaimer
This website is for educational and informational purposes only. The information provided is not intended to diagnose, treat, cure, or prevent any disease. Always consult with a qualified healthcare professional before using any peptide or supplement.