Insulin Dosing Calculator
Insulin: Essential glucose-regulating peptide hormone.
Pre-filled with the most-reported community reconstitution protocol for Insulin. See how 1 mL and 2 mL of bacteriostatic water change concentration and syringe-draw volume, then adjust the calculator below for your own vial.
Quick answer · Community-reported standard
A 5,000 IU vial of Insulin reconstituted with 2 mL of bacteriostatic water yields a concentration of 2,500 IU/mL. At that concentration, a 1 IU dose of Insulin equals 0 units on a U-100 insulin syringe (0.000 mL). Insulin is typically administered once daily via subcutaneous injection.
Insulin reconstitution: 1 mL vs 2 mL bac water
Bacteriostatic water volume is flexible. Less water means higher concentration and smaller injection volumes; more water means lower concentration and easier dose precision. Both options below are valid for a 5,000 IU vial.
| BAC water added | Concentration | Volume per 1 IU dose | Draw on U-100 syringe (units) |
|---|---|---|---|
| 1 mL | 5,000 IU/mL | 0.000 mL | 0 units |
| 2 mL | 2,500 IU/mL | 0.000 mL | 0 units |
Calculate your Insulin dose
Alternative Insulin protocols
Beyond the default above, Insulin is also reported in the following protocols. Use these as starting points and recalculate with the tool above.
Type 2 Diabetes Add-On Protocol
Community- Dose
- Starting 10 IU basal insulin, titrated to fasting glucose target
- Frequency
- Once daily (basal) or with meals if needed
- Duration
- Ongoing
- Route
- Subcutaneous injection
Initiated when oral medications and lifestyle modifications are insufficient
Bodybuilding Anabolic Protocol (High Risk)
Community- Dose
- 4-10 IU rapid-acting insulin
- Frequency
- Pre or post-workout
- Duration
- Training cycles (variable)
- Route
- Subcutaneous injection
EXTREMELY DANGEROUS - bodybuilding use carries risk of fatal hypoglycemia; discussed in r/steroids
Insulin Pump (CSII) Protocol
Community- Dose
- Individualized basal rates + bolus calculations
- Frequency
- Continuous basal + meal-time boluses
- Duration
- Ongoing
- Route
- Continuous subcutaneous infusion
Continuous subcutaneous insulin infusion via pump; discussed extensively in r/diabetes and r/Type1Diabetes
Type 1 diabetes management
Clinical- Dose
- Individualized; typically 0.4-1.0 IU/kg/day total (basal-bolus split)
- Frequency
- Basal once or twice daily; bolus with each meal
- Duration
- Chronic lifelong therapy
Intensive therapy targets HbA1c ~7% with frequent glucose monitoring
Type 2 diabetes management
Clinical- Dose
- Individualized; starting basal 0.1-0.2 IU/kg/day, titrated to fasting glucose target
- Frequency
- Basal once daily; add prandial insulin if needed
- Duration
- Chronic therapy when oral agents insufficient
Often combined with metformin or GLP-1 receptor agonists
Insulin reconstitution & storage
Pre-filled pens and vials do not require reconstitution; insulin is supplied as ready-to-use solution or suspension
Unopened: refrigerate at 2-8°C for up to 2 years; do not freeze. In-use: store below 25-30°C and discard per product-specific windows (typically 15-30 days)
Insulin dosing FAQ
How much bacteriostatic water should I add to a 5,000 IU vial of Insulin?
The community standard is 2 mL of bacteriostatic water for a 5,000 IU Insulin vial. That gives a concentration of 2,500 IU/mL, so a 1 IU dose is 0 units on a U-100 insulin syringe. Adding 1 mL instead doubles the concentration to 5,000 IU/mL and halves the draw to 0 units. Less water = smaller injection volume but harder to measure precisely.
How many syringe units is a 1 IU dose of Insulin?
On a standard U-100 insulin syringe, a 1 IU dose of Insulin is 0 units when the 5,000 IU vial is reconstituted with 2 mL of bacteriostatic water (2,500 IU/mL). If you use 1 mL of bac water instead, draw 0 units (5,000 IU/mL).
What is the standard Insulin dose?
Community-reported protocols for Insulin typically use 0.5–1 IU once daily via Subcutaneous injection. 1 IU is a common starting dose. Standard diabetes management; basal insulin (glargine/detemir) plus rapid-acting (lispro/aspart) with meals
How long does a vial of Insulin last at 1 IU once daily?
A 5,000 IU vial of Insulin contains roughly 10000 doses at 1 IU per injection. At once daily dosing, that is approximately 10000 days (about 1429 weeks) of supply per vial. Reconstituted Insulin should generally be used within 28 days when refrigerated.
Where do you inject Insulin?
Insulin is typically injected subcutaneous injection. Common sites reported in the literature and by users include: Abdomen (fastest absorption), Upper arm, Thigh (slower early exposure), Buttock. Rotate sites with each injection to reduce localized irritation.
Can I use sterile water instead of bacteriostatic water for Insulin?
Bacteriostatic water (containing 0.9% benzyl alcohol as a preservative) is strongly preferred for multi-dose vials like Insulin because it inhibits microbial growth and lets a single vial be used over multiple weeks. Sterile water has no preservative and should generally be reserved for single-use preparations only.
More on Insulin
Medical Disclaimer
This website is for educational and informational purposes only. The information provided is not intended to diagnose, treat, cure, or prevent any disease. Always consult with a qualified healthcare professional before using any peptide or supplement.