OS-01 (Peptide 14): Dosing Protocols
Dosing guidelines, reconstitution, and administration information
๐TL;DR
- โข3 dosing protocols documented
- โขReconstitution instructions included
- โขStorage: Store OneSkin products at room temperature, away from direct sunlight and extreme heat. Follow manufacturer storage instructions on product packaging. No refrigeration required for commercial formulations.
Protocol Quick-Reference
Topical senomorphic skin treatment (cosmetic)
Dosing
Amount
Per product instructions (proprietary concentration)
Frequency
Twice daily
Duration
Ongoing (minimum 8-12 weeks for results)
Step-wise Titration
Administration
Route
TopicalSchedule
N/A (topical application)
Timing
Apply to clean skin before moisturizer; morning and evening
Cycle
Duration
Ongoing (continuous use)
Repeatable
Yes
๐ก Key Considerations
- โCosmetic product, not an FDA-approved drug
- โExact peptide concentration is proprietary and undisclosed
- โAvailable exclusively through OneSkin commercial products
- โNo reconstitution or injection required
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| Purpose | Dose | Frequency | Duration | Notes |
|---|---|---|---|---|
| Twice daily | 12 weeks | Cosmetic product application; not a pharmaceutical dosing protocol. Concentration of OS-01 in formulation is proprietary. | ||
| Daily | 12 weeks | Pilot study protocol. Control group used commercial moisturizer without OS-01. | ||
| Twice daily | 12 weeks | Single-arm study without control group. Product contains additional active ingredients alongside OS-01. |
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๐Reconstitution Instructions
OS-01 is available only in pre-formulated topical products (moisturizers and lotions) from OneSkin. No reconstitution is required. The peptide is not available as a standalone powder or injectable.
๐งStorage Requirements
Store OneSkin products at room temperature, away from direct sunlight and extreme heat. Follow manufacturer storage instructions on product packaging. No refrigeration required for commercial formulations.
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Before You Begin
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Important Disclaimer#
OS-01 (Peptide 14) is a cosmetic ingredient, not an FDA-approved drug. The information below reflects how OS-01 has been used in published clinical trials and commercial products. There are no pharmaceutical dosing guidelines for this compound. The peptide concentration in commercial products is proprietary and not publicly disclosed.
Application Information#
OS-01 differs from most peptides covered on this site in that it is exclusively available as a pre-formulated topical cosmetic product. It is not sold as a standalone peptide for reconstitution or injection.
Commercial Product Forms#
OneSkin markets several products containing OS-01:
- OS-01 FACE -- moisturizer for facial application
- OS-01 BODY -- body lotion formulation
- OS-01 EYE -- periorbital-specific formulation
Clinical Trial Application Protocols#
In published clinical trials, the following protocols were used:
Face Application (2024 RCT): Participants applied OS-01 facial formulation twice daily for 12 weeks. The split-face design had participants use the active formulation on one side and vehicle control on the other.
Body Application (2025 RCT): Women aged 60-90 applied OS-01 body lotion to the body once daily for 12 weeks.
Eye Application (2025 Study): Participants applied OS-01 EYE to the periorbital area twice daily for 12 weeks.
Concentration and Dose#
The exact concentration of OS-01 peptide in commercial formulations is proprietary and has not been disclosed in published literature. The peptide's amino acid sequence (Decapeptide-52) is similarly proprietary, making independent formulation impossible.
Storage Guidelines#
Commercial OneSkin products should be stored at room temperature, protected from direct sunlight and extreme heat. No special storage conditions such as refrigeration are required for the finished commercial products. Shelf life follows standard cosmetic product guidelines as indicated on packaging.
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Medical Disclaimer
This website is for educational and informational purposes only. The information provided is not intended to diagnose, treat, cure, or prevent any disease. Always consult with a qualified healthcare professional before using any peptide or supplement.