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Tesamorelin Dosing Calculator

Tesamorelin (Egrifta): FDA-approved GHRH analog for HIV lipodystrophy.

Pre-filled with the most-reported community reconstitution protocol for Tesamorelin. See how 1 mL and 2 mL of bacteriostatic water change concentration and syringe-draw volume, then adjust the calculator below for your own vial.

Quick answer ยท Community-reported standard

A 5 mg vial of Tesamorelin reconstituted with 2 mL of bacteriostatic water yields a concentration of 2.50 mg/mL. At that concentration, a 2 mg dose of Tesamorelin equals 80 units on a U-100 insulin syringe (0.800 mL). Tesamorelin is typically administered once daily via subcutaneous.

Tesamorelin reconstitution: 1 mL vs 2 mL bac water

Bacteriostatic water volume is flexible. Less water means higher concentration and smaller injection volumes; more water means lower concentration and easier dose precision. Both options below are valid for a 5 mg vial.

BAC water addedConcentrationVolume per 2 mg doseDraw on U-100 syringe (units)
1 mL5.00 mg/mL0.400 mL40 units
2 mL2.50 mg/mL0.800 mL80 units
Based on a 5 mg vial of Tesamorelin reconstituted with bacteriostatic water. Insulin-syringe units assume a standard U-100 syringe (100 units = 1 mL).

Calculate your Tesamorelin dose

Alternative Tesamorelin protocols

Beyond the default above, Tesamorelin is also reported in the following protocols. Use these as starting points and recalculate with the tool above.

Beginner/Conservative Protocol

Community
Dose
1 mg
Frequency
Once daily
Duration
12-16 weeks
Route
Subcutaneous

Half the standard dose; used by new users to assess tolerance before potentially increasing to 2 mg

Maintenance Protocol

Community
Dose
1-2 mg
Frequency
5 days per week
Duration
Ongoing with periodic breaks
Route
Subcutaneous

Reduced frequency for long-term use; some users find 5 days on, 2 days off sufficient to maintain results

Tesamorelin + Ipamorelin Stack

Community
Dose
1-2 mg tesamorelin + 200 mcg ipamorelin
Frequency
Once daily before bed
Duration
12-16 weeks
Route
Subcutaneous

Combines GHRH analog with GHRP for enhanced GH output; less common due to tesamorelin cost

FDA-Approved Protocol: HIV-Associated Lipodystrophy

Clinical
Dose
2 mg subcutaneous injection
Frequency
Once daily
Duration
Ongoing; reassess periodically based on clinical response

Inject into abdomen. Rotate injection sites. This is the only FDA-approved dosing regimen.

NASH/Hepatic Steatosis Research Protocol

Clinical
Dose
2 mg subcutaneous injection
Frequency
Once daily
Duration
12 months in the GILT trial

Investigational use only. Same dose as approved indication used in clinical research for hepatic steatosis.

Tesamorelin reconstitution & storage

Reconstitute with the sterile water for injection provided in the kit. For Egrifta SV, use the pre-filled syringe of diluent provided. Inject the diluent slowly into the vial, then roll gently between palms for 30 seconds to dissolve. Do not shake. The reconstituted solution should be clear and colorless. Use immediately after reconstitution. Do not freeze reconstituted solution.

Unreconstituted vials: Store at room temperature 20-25 degrees C (68-77 degrees F). Protect from light. Reconstituted solution: Use immediately. Do not freeze. Discard unused portion.

Tesamorelin dosing FAQ

How much bacteriostatic water should I add to a 5 mg vial of Tesamorelin?

The community standard is 2 mL of bacteriostatic water for a 5 mg Tesamorelin vial. That gives a concentration of 2.50 mg/mL, so a 2 mg dose is 80 units on a U-100 insulin syringe. Adding 1 mL instead doubles the concentration to 5.00 mg/mL and halves the draw to 40 units. Less water = smaller injection volume but harder to measure precisely.

How many syringe units is a 2 mg dose of Tesamorelin?

On a standard U-100 insulin syringe, a 2 mg dose of Tesamorelin is 80 units when the 5 mg vial is reconstituted with 2 mL of bacteriostatic water (2.50 mg/mL). If you use 1 mL of bac water instead, draw 40 units (5.00 mg/mL).

What is the standard Tesamorelin dose?

Community-reported protocols for Tesamorelin typically use 2 mg once daily via Subcutaneous. 2 mg is a common starting dose. FDA-approved dose for HIV lipodystrophy; adopted by community for general visceral fat reduction. Injected in abdominal area before bed.

How long does a vial of Tesamorelin last at 2 mg once daily?

A 5 mg vial of Tesamorelin contains roughly 2 doses at 2 mg per injection. At once daily dosing, that is approximately 2 days (about 0 weeks) of supply per vial. Reconstituted Tesamorelin should generally be used within 28 days when refrigerated.

Where do you inject Tesamorelin?

Tesamorelin is typically injected subcutaneous. Common sites reported in the literature and by users include: Subcutaneous (abdomen only per FDA-approved labeling). Rotate sites with each injection to reduce localized irritation.

Can I use sterile water instead of bacteriostatic water for Tesamorelin?

Bacteriostatic water (containing 0.9% benzyl alcohol as a preservative) is strongly preferred for multi-dose vials like Tesamorelin because it inhibits microbial growth and lets a single vial be used over multiple weeks. Sterile water has no preservative and should generally be reserved for single-use preparations only.

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Medical Disclaimer

This website is for educational and informational purposes only. The information provided is not intended to diagnose, treat, cure, or prevent any disease. Always consult with a qualified healthcare professional before using any peptide or supplement.