GUBamy Dosing Calculator
GUBamy (GUB014295): dual amylin/calcitonin receptor agonist (DACRA) by Gubra.
Pre-filled with the most-reported clinical reconstitution protocol for GUBamy. See how 1 mL and 2 mL of bacteriostatic water change concentration and syringe-draw volume, then adjust the calculator below for your own vial.
Quick answer · Clinical protocol
A 10 mg vial of GUBamy reconstituted with 2 mL of bacteriostatic water yields a concentration of 5.00 mg/mL. At that concentration, a 1 mg dose of GUBamy equals 20 units on a U-100 insulin syringe (0.200 mL). GUBamy is typically administered once weekly.
GUBamy reconstitution: 1 mL vs 2 mL bac water
Bacteriostatic water volume is flexible. Less water means higher concentration and smaller injection volumes; more water means lower concentration and easier dose precision. Both options below are valid for a 10 mg vial.
| BAC water added | Concentration | Volume per 1 mg dose | Draw on U-100 syringe (units) |
|---|---|---|---|
| 1 mL | 10.00 mg/mL | 0.100 mL | 10 units |
| 2 mL | 5.00 mg/mL | 0.200 mL | 20 units |
Calculate your GUBamy dose
GUBamy reconstitution & storage
Formulation details not publicly disclosed. Administered as a subcutaneous injection in clinical trials.
Storage requirements not publicly disclosed. Likely requires refrigeration based on peptide formulation standards.
GUBamy dosing FAQ
How much bacteriostatic water should I add to a 10 mg vial of GUBamy?
The community standard is 2 mL of bacteriostatic water for a 10 mg GUBamy vial. That gives a concentration of 5.00 mg/mL, so a 1 mg dose is 20 units on a U-100 insulin syringe. Adding 1 mL instead doubles the concentration to 10.00 mg/mL and halves the draw to 10 units. Less water = smaller injection volume but harder to measure precisely.
How many syringe units is a 1 mg dose of GUBamy?
On a standard U-100 insulin syringe, a 1 mg dose of GUBamy is 20 units when the 10 mg vial is reconstituted with 2 mL of bacteriostatic water (5.00 mg/mL). If you use 1 mL of bac water instead, draw 10 units (10.00 mg/mL).
What is the standard GUBamy dose?
Clinical protocols for GUBamy typically use 1 mgâ6 mg once weekly via subcutaneous injection. 1 mg is a common starting dose. Early-stage dosing only. Phase 2 doses may differ. Dose escalation likely required based on GI tolerability, consistent with the amylin analog class.
How long does a vial of GUBamy last at 1 mg once weekly?
A 10 mg vial of GUBamy contains roughly 10 doses at 1 mg per injection. At once weekly dosing, that is approximately 70 days (about 10 weeks) of supply per vial. Reconstituted GUBamy should generally be used within 28 days when refrigerated.
Where do you inject GUBamy?
GUBamy is typically injected subcutaneously. Common sites reported in the literature and by users include: Abdomen, Thigh. Rotate sites with each injection to reduce localized irritation.
Can I use sterile water instead of bacteriostatic water for GUBamy?
Bacteriostatic water (containing 0.9% benzyl alcohol as a preservative) is strongly preferred for multi-dose vials like GUBamy because it inhibits microbial growth and lets a single vial be used over multiple weeks. Sterile water has no preservative and should generally be reserved for single-use preparations only.
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Medical Disclaimer
This website is for educational and informational purposes only. The information provided is not intended to diagnose, treat, cure, or prevent any disease. Always consult with a qualified healthcare professional before using any peptide or supplement.