Taspoglutide Dosing Calculator

Dose

20 mg subcutaneous injection once weekly. The higher dose used across T-emerge trials.

Frequency

Once weekly subcutaneous injection

Duration

24-52 weeks in clinical trials

Never approved for clinical use. HbA1c reduction of -1.31% in T-emerge 2. Greater nausea and vomiting rates (59% nausea, 37% vomiting) compared to 10 mg dose.

How much bacteriostatic water should I add to a 5 mg vial of Taspoglutide?

The community standard is 2 mL of bacteriostatic water for a 5 mg Taspoglutide vial. That gives a concentration of 2.50 mg/mL, so a 10 mg dose is 400 units on a U-100 insulin syringe. Adding 1 mL instead doubles the concentration to 5.00 mg/mL and halves the draw to 200 units. Less water = smaller injection volume but harder to measure precisely.

How many syringe units is a 10 mg dose of Taspoglutide?

On a standard U-100 insulin syringe, a 10 mg dose of Taspoglutide is 400 units when the 5 mg vial is reconstituted with 2 mL of bacteriostatic water (2.50 mg/mL). If you use 1 mL of bac water instead, draw 200 units (5.00 mg/mL).

What is the standard Taspoglutide dose?

Clinical protocols for Taspoglutide typically use 10 mg–2 mg once weekly via subcutaneous injection. 10 mg is a common starting dose. Never approved for clinical use. HbA1c reduction of -1.24% in T-emerge 2. Lower dose had somewhat fewer GI side effects than 20 mg.

Where do you inject Taspoglutide?

Taspoglutide is typically injected subcutaneously. Common sites reported in the literature and by users include: Abdomen, Thigh. Rotate sites with each injection to reduce localized irritation.

Can I use sterile water instead of bacteriostatic water for Taspoglutide?

Bacteriostatic water (containing 0.9% benzyl alcohol as a preservative) is strongly preferred for multi-dose vials like Taspoglutide because it inhibits microbial growth and lets a single vial be used over multiple weeks. Sterile water has no preservative and should generally be reserved for single-use preparations only.