ARA-290 Dosing Calculator
ARA-290 (Cibinetide): EPO-derived neuroprotective peptide.
Pre-filled with the most-reported community reconstitution protocol for ARA-290. See how 1 mL and 2 mL of bacteriostatic water change concentration and syringe-draw volume, then adjust the calculator below for your own vial.
Quick answer · Community-reported standard
A 10 mg vial of ARA-290 reconstituted with 2 mL of bacteriostatic water yields a concentration of 5.00 mg/mL. At that concentration, a 2 mg dose of ARA-290 equals 40 units on a U-100 insulin syringe (0.400 mL). ARA-290 is typically administered once daily via subcutaneous.
ARA-290 reconstitution: 1 mL vs 2 mL bac water
Bacteriostatic water volume is flexible. Less water means higher concentration and smaller injection volumes; more water means lower concentration and easier dose precision. Both options below are valid for a 10 mg vial.
| BAC water added | Concentration | Volume per 2 mg dose | Draw on U-100 syringe (units) |
|---|---|---|---|
| 1 mL | 10.00 mg/mL | 0.200 mL | 20 units |
| 2 mL | 5.00 mg/mL | 0.400 mL | 40 units |
Calculate your ARA-290 dose
Alternative ARA-290 protocols
Beyond the default above, ARA-290 is also reported in the following protocols. Use these as starting points and recalculate with the tool above.
Low-Dose Neuroprotective Protocol
Community- Dose
- 1-2 mg
- Frequency
- Once daily
- Duration
- 4-8 weeks
- Route
- Subcutaneous
Some community members report using lower doses for general neuroprotective purposes
Sarcoidosis SFN Pilot Study (IV)
Clinical- Dose
- 2 mg
- Frequency
- Three times weekly
- Duration
- 4 weeks
Intravenous administration in sarcoidosis patients
Sarcoidosis SFN Follow-up (SC)
Clinical- Dose
- 4 mg
- Frequency
- Once daily
- Duration
- 28 days
Subcutaneous self-administration
Type 2 Diabetes Neuropathy (SC)
Clinical- Dose
- 4 mg
- Frequency
- Once daily
- Duration
- 28 days
Subcutaneous self-administration with 28-day observation follow-up
ARA-290 reconstitution & storage
In clinical trials, ARA-290 was provided as a sterile aqueous solution ready for injection. For research use, reconstitute lyophilized peptide with sterile water or bacteriostatic water to desired concentration.
Store lyophilized peptide at -20C. Reconstituted solutions should be stored at 2-8C and used within 14 days. Protect from light.
ARA-290 dosing FAQ
How much bacteriostatic water should I add to a 10 mg vial of ARA-290?
The community standard is 2 mL of bacteriostatic water for a 10 mg ARA-290 vial. That gives a concentration of 5.00 mg/mL, so a 2 mg dose is 40 units on a U-100 insulin syringe. Adding 1 mL instead doubles the concentration to 10.00 mg/mL and halves the draw to 20 units. Less water = smaller injection volume but harder to measure precisely.
How many syringe units is a 2 mg dose of ARA-290?
On a standard U-100 insulin syringe, a 2 mg dose of ARA-290 is 40 units when the 10 mg vial is reconstituted with 2 mL of bacteriostatic water (5.00 mg/mL). If you use 1 mL of bac water instead, draw 20 units (10.00 mg/mL).
What is the standard ARA-290 dose?
Community-reported protocols for ARA-290 typically use 2 mgâ4 mg once daily via Subcutaneous. 2 mg is a common starting dose. Based on clinical trial dosing; very few community users report self-administering ARA-290 due to limited availability
How long does a vial of ARA-290 last at 2 mg once daily?
A 10 mg vial of ARA-290 contains roughly 5 doses at 2 mg per injection. At once daily dosing, that is approximately 5 days (about 1 weeks) of supply per vial. Reconstituted ARA-290 should generally be used within 28 days when refrigerated.
Where do you inject ARA-290?
ARA-290 is typically injected subcutaneous. Common sites reported in the literature and by users include: Subcutaneous (abdomen), Subcutaneous (thigh), Intravenous (clinical setting). Rotate sites with each injection to reduce localized irritation.
Can I use sterile water instead of bacteriostatic water for ARA-290?
Bacteriostatic water (containing 0.9% benzyl alcohol as a preservative) is strongly preferred for multi-dose vials like ARA-290 because it inhibits microbial growth and lets a single vial be used over multiple weeks. Sterile water has no preservative and should generally be reserved for single-use preparations only.
More on ARA-290
Medical Disclaimer
This website is for educational and informational purposes only. The information provided is not intended to diagnose, treat, cure, or prevent any disease. Always consult with a qualified healthcare professional before using any peptide or supplement.